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中
Gallery BeneHMOs® 2'-Fucosyllactose(2'-FL)
BeneHMOs® 2'-Fucosyllactose(2'-FL)
ingredient_innovation
Wuhan CASOV Green Biotech Co., Ltd.

Company Website

http://www.casov.net/

Company Introduction

Wuhan CASOV Green Biotechnology Co., Ltd. was established in December 2010 and recognized as a National High-tech Enterprise in October 2014. With strong technical expertise, the company operates as the managing body of the Biotechnology Engineering Center under the Hubei Industrial Technology Innovation and Incubation Center of the Chinese Academy of Sciences. It also collaborates closely with senior research teams from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, to drive continuous innovation. Leveraging core technologies such as AI computing, multi-omics, synthetic biology, microbial fermentation, and encapsulation co-delivery systems, the company provides high-quality cosmetic ingredients, encapsulation technologies, and mechanistic research on active ingredients, along with tailored application solutions.
Focusing on functional raw materials, the company is actively expanding into the functional cosmetic and personal care ingredient sect

Launch Date

2025-10

Weight/Volume per Pack

100g

Price per Item

100

Storage requirements

常温储存(Normal Temperature Preservation)

Background and basic information of the product

本产品基于极地生物(如弓头鲸、北极熊)在极端环境下的高效自我修复机制研发。研究发现,这些生物体内高表达的CIRBP(冷诱导RNA结合蛋白)是其长寿与抗损伤的关键。通过合成生物学技术,我们成功开发出BeneHMOs® 2'-FL,这是一种能激活人体CIRBP表达的活性成分,从基因层面增强肌肤自主修复能力。除此之外,其还属于母乳除油脂和糖类之外的第三大营养成分,目前产品已获国家化妆品原料备案(国妆原备字20250130),2024年8月5日母公司独立申报的营养强化剂也正式获批,具备绿色、可持续、高效的特点,代表国产合成生物学在护肤领域的前沿突破。

Product Images

Please briefly describe the key innovations of your product and provide evidence of its value from all dimensions

本产品的核心创新在于首次将极地生物的长寿修复机制——CIRBP蛋白系统——转化为可应用于人类肌肤的活性成分BeneHMOs® 2'-FL,实现了从“舒缓表象”到“基因编程式修复”的跨越。
其关键创新与多维价值包括:
机制创新:直击细胞自我修复能力衰退的核心。2'-FL能激活人体细胞的CIRBP表达(提升117%),模拟弓头鲸的高效修复程序,从基因层面修复DNA损伤(如UVA导致的断裂),根源抵御老化。
功效创新:以CIRBP为“总开关”,系统性调控抗炎、屏障、抗氧化三大通路。实验证实其能从源头抑制NF-κB炎症通路、显著增强皮肤屏障功能(提升含水量45.04%)、并提升机体抗氧化酶活性,实现全链路修复。
场景与合规创新:基于CIRBP的低温活性,开辟“低温高效修复”新场景。产品已完成化妆品原料备案并获新食品原料批准,具备国家级生物制造背书,实现了前沿科学向安全合规原料的关键转化。

Product Images

Please briefly describe the product's application areas

主要应用于功效护肤领域、婴童乳品领域,包括:冬季冷修复系列、DNA级晒后修复精华、修复抗老双效精华、敏肌屏障重建系列、男士剃须后修复、婴童奶粉等。典型案例为“光损修复精华”,可在24小时内减轻紫外线导致的泛红,并从DNA层面修复光损伤,适用于户外、医美术后等高光损场景。

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